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- 品牌：賽默飛
- 產(chǎn)地：國外
- 型號：詳詢
- 貨號：PA5-116785
- 發(fā)布日期： 2022-08-29
- 更新日期： 2024-08-12
| 產(chǎn)地 | 國外 |
| 品牌 | 賽默飛 |
| 貨號 | PA5-116785 |
| 保存條件 | -20° C, Avoid Freeze/Thaw Cycles |
| 用途 | 詳詢 |
| 應用范圍 | ICC/IF WB IHC (P) |
| 抗原來源 | 詳詢 |
| CAS編號 | |
| 保質期 | 詳詢 |
| 抗體名 | Histone H3ac (pan-acetyl) Polyclonal Antibody |
| 是否單克隆 | 否 |
| 克隆性 | 是 |
| 靶點 | 詳詢 |
| 適應物種 | Human, Mouse, Rat |
| 形態(tài) | Liquid |
| 宿主 | Rabbit |
| 標記物 | 詳詢 |
| 包裝規(guī)格 | 詳詢 |
| 純度 | 詳詢% |
| 亞型 | IgG |
| 標識物 | 詳詢 |
| 濃度 | 1.1 mg/mL% |
| 免疫原 | 詳詢 |
| 是否進口 | 是 |
產(chǎn)品信息
|
應用 |
建議稀釋比 |
免疫印跡 (WB) |
1:500-1:2,000 |
免疫組化（石蠟） (IHC (P)) |
1:50-1:200 |
免疫細胞化學 (ICC/IF) |
1:50-1:200 |
|
產(chǎn)品規(guī)格
|
|
|---|---|
種屬反應 |
Human, Mouse, Rat |
宿主/亞型 |
Rabbit / IgG |
分類 |
Polyclonal |
類型 |
Antibody |
抗原 |
A synthetic peptide of human Acetyl-Histone H3-K9/K14/K18/K23/K27 |
偶聯(lián)物 |
Unconjugated |
形式 |
Liquid |
濃度 |
1.1 mg/mL |
純化類型 |
Affinity chromatography |
保存液 |
PBS, pH 7.3, with 50% glycerol |
內含物 |
0.02% sodium azide |
保存條件 |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2901416 |
產(chǎn)品詳細信息
Positive Samples: HeLa, NIH/3T3, C6
靶標信息
Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
